Mangosteen
20 TO 1 EXTRACT
Ingredients: http://i.b5z.net/i/u/2010009/i/Mangosteen_Label_--20_to_1_extract.pdf
Diseases: Research from medical universities all over the world has shown Xanthones in the Mangosteen fruit contain elements that literally help to correct and kill many diseases that occur today.
Immune System: Protects against pathogens, sepsis, influenza, pneumonia, tuberculosis, AIDS, and diverticulosis. Anti-bacterial, anti-viral, anti-fungal. Laboratory demonstrated to interfere with HIV protease, which keeps the virus immature and incapable of infections. Thai study demonstrated effectiveness against staphylococcus aureus bacteria. Polysaccharides in the rind stimulate phagocytic immune cells (PMNs and monocytes). Effective against salmonella, typhus and tuberculosis bacteria.
Asian healers have used Mangosteen for centuries for syphilis, malaria, and amebic dysentery. In South America, it is used for intestinal worm infestations.
Anti-Tumor Properties: Catechins in Mangosteen: Prevent formation of carcinogenic compounds by blocking co-carcinogens. Turn up body's natural detoxification defenses. Suppress cancer promotion or growth.
Gastro-Intestinal System: Dysentery, GI pathogens, diverticulosis, histamine and serotonin blocking capacity. Reduces excess stomach acid. Anti-allergic effect. Anti-stomach ulcer.
Respiratory System: Mangosteen study in September 2002 reported that it is an anti-inflammatory and anti-allergenic agent. Relevant for asthma. Xanthoses modulate IGE, antibody class involved in allergic reactions. Mangosteen can accomplish what we now use several drugs to do. Ideal product to use daily to protect our respiratory systems integrity.
The Central Nervous System: Dr. Nakahatas research with glial cells (central nervous systems cells) suggest that Mangosteen could produce a therapeutic effect in both treatment and prevention of Parkinsons and Alzheimers disease.
Skin: Mangosteen used for centuries to treat eczema, dermatitis, wounds, ringworm, acne, impetigo, and growth disorders of dermis (psoriasis or seborrhea) skin cancer and sun damage.
Folk Medicine Remedies: Antimicrobial/anti-inflammatory powers. Treating eczematous and hyperkeratotic skin conditions. In Caribbean, tonic for fatigue and malaise. Controlling fever.
Prescription Drugs: Do you take prescription drugs? In our humble opinion, the mangosteen equals or outperforms the following prescriptions and over-the-counter drugs:
- Nexium, Prevacid, Aciphex
- Zantec, Pepcid, other H2 blockers
- Allegra, Zyrtec, Claritin, other antihistamines
- Lotrisone, Topicort, Cutivate, other topical corticosteroids
- Valium, Zanaz, other minor tranquilizers
- Tegretol, Neurontin, other anti-epileptic drugs when used for chronic pain
- Anusol, other hemorrhoid preparations
- Prozac, Zyloft, Paxil, Lexapro, other anti-depressants when used for dysthymia or anxiety
- Vicodin, Percocet, Duragesic patches, other narcotics
- Celebrex, Vioxx, Bextra, Naproxen, Arthrotec, Ibuprofen, other anti-inflammatories
- Ultram, Talwin, other non-opiod pain preparations
- Midrin, Fioricet, Imitrex, Amerge, Maxalt, Zomig, other migraine preparations
- Lupitor, Zocor, Pravacol, other lipid-lowering agents
- Valtrex
- Aricept, Cognex, other Alzheimer's preparations
- Singulair
- Prednisone
Mangosteen - contains the finest in Mangosteen Pericarp. Mangosteen is a fruit found in countries such as Thailand, India, Malaysia, Vietnam and the Philippines. It grows in areas such as Hawaii and Australia. The fruit consist of 3 major parts.
The Mangosteen Pericarp, which is the rind or peel, contains the highest level of xanthones. The pulp, which is the fruit, known for being one of the tastiest fruits in the world. The seeds found in the pulp. Mangosteen has compounds that have antioxidant, anti-bacterial, anti-fungal, and anti-tumor activity. Laboratory tests have indicated that extracts of mangosteen have activity against several cancer cell lines including breast, liver, and leukemia. Mangosteen also contains anti-histamine and anti-inflammatory properties. Mangosteen has been used for many years as a medicinal treatment for diarrhea, skin infection and wounds in South Asia.
The latest in scientific research shows mangosteen contains a class of naturally occurring polyphenolic compound known as xanthones. Xanthones provide beneficial effects on cardiovascular diseases, including ischemic heart disease, atherosclerosis, hypertension, and thrombosis. Mangosteen shows vasorelaxant properties. Mycobacterium tuberculosis, Staphylococcus aureus, Mangosteen has shown inhibitory action against these organisms. Mangosteen is highly effective in weak immune system. There are several compounds found in the Mangosteen that appear to make this fruit so active as a nutritional component for the body.
Xanthones are broken down even further into mangostin, mangostenol, mangostenone A, Mangostenone B, trapezifolixanthone, tovophyllin B, alpha- and beta-mangostins, garcinone B, mangostinone, mangostanol and the flavonoid epicatechin. A study of the antiproliferation, antioxidation and induction of apoptosis by Garcinia mangostana on SKBR3 human breast cancer cell line, showed SKBR3 cells were cultured in the presence of mangosteen extract at various concentrations. Mangosteen showed a dose dependent inhibition of cell proliferation. We found that an antiproliferative effect of mangosteen was associated with apoptosis on breast cancer cell line by determinations of morphological changes and oligonucleosomal DNA fragments. Mangosteen also was found to inhibit ROS production. These investigations suggest that the mangosteen had strong anti-proliferation, potent anti-oxidation and induction of apoptosis. Mangosteen has potential for cancer chemoprevention, which is dose dependent as well as exposure time dependent. The ethanol extract of Mangosteen showed potent inhibitory activity against HIV-1 protease. The activity-guided purification of the extract resulted in the isolation of two active known compounds. The chemical structures of the isolated compounds were established by spectroscopic analysis as mangostin and gamma-mangostin.
Potential Benefits of Mangosteen
Anti-viral
Anti-bacterial
Free radical fighter
Cardio support
Immune system Enhancer
Powerful antioxidant
Skin rashes, infections and wounds
Diarrhea
Anti-inflammatory
Vasorelaxant
Mangosteen contains:
100% Pure Xanthones Rich Mangosteen Pericarp (hull powder) - No Fillers, No Additives, No Preservatives, No Artificial Colors. Gelatin capsule.
References and Studies: Tapiero, H., et. al. "Polyphenols: do they play a role in the prevention of human pathologies?" Biomedicine & Pharmacotheraphy; 2002, 56 (4):200-207
Huang, D., et. al. "High-throughout assay of oxygen radical absorbency capacity using multichannel liquid handling system coupled with a microplate florescence reader in 96 we format." Journal of Agricultural and Food Chemistry: 2002 50 (16): 4437-4444
Mangosteen in the Columbia Encyclopedia, 6 th edition, Columbia University Press 2003
Parkinson. R. "Mangoes, Lychees and Mangosteen.: Chinese Cuisine 2004
Nakatani, K. , et. al. "gamma-Mangostin inhibits IkappaB Kinase Activity with and decreases Lipopolysaccaride-induced cyclooxgenanase-2 Gene Expression in C6 Rat glioma Cells." Molecular Pharmacology; June 24, 2004
Jiang, D.J. e. al. " Pharmacological effects of xanthones as cardiovascular protective agents." Cardiovascular Drug Reviews , 2004, 22(2):91-102
Biochem Pharmacol, 2002 Jan 1;63(1):73-9
Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives - J. Nat Prod 1997 May; 60 (5):519-24
Active constituents against HIV-1 protease from Mangosteen- Planta Med 1996 Aug;62(4):381-2
Mangostin inhibits the oxidative modification of human low density lipoprotein- Free radic Res. 1995 Aug.:23(2):175-84
Antiproliferation, antioxidation and induction of apoptosis by Garcinia mangostana on SKBR3 human breast cancer cell line J.Ethnopharmacol, 2004 Jan:90(1):161-6
Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines
J.Nat Prod. 2003 Aug;55(8):1124-7
